solutions for LDN

Get Low Dose Naltrexone (LDN)
Fast, Safe, and Doctor-Guided.

A non-opioid prescription option commonly used in chronic pain, inflammation, and immune-related conditions — prescribed by licensed clinicians through secure telehealth.
Start Feeling Better in Three Easy Steps

1. Quick Online
Screening

See if you may qualify in 2 minutes
- no referral needed.

2. Meet with a Licensed Clinician

A licensed provider through our partner medical practice reviews your history and designs your personalized LDN plan.

3. Get LDN Shipped
to Your Door

Your prescription is filled by a trusted compounding pharmacy.

What is LDN

LDN is a low-dose formulation of a long-used medication that some clinicians prescribe off-label to support patients with chronic pain, inflammation, and immune-related conditions.

In low doses, naltrexone is thought to briefly interact with opioid receptors, which may influence how the nervous and immune systems communicate.

LDN is non-opioid, non-habit-forming, and prescribed under clinician supervision when appropriate.

Benefits You May Notice

Less Pain & Inflammation - May help support calmer immune and nerve signaling.
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Better Energy & Mood - Supports natural endorphin production.
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Sharper Focus - Some patients report improvements in mental clarity.
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Restored Balance - Helps regulate immune and hormonal function.
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Results vary; most patients notice improvement within 4–8 weeks.

Get Started

To get started enter your name and email below. On the next page you can book a time with our tele-health specialist.

Over 60 published studies have explored LDN in immune and inflammatory pathways.

Low-dose, non-habit-forming, with decades of safety data.

We address the root drivers of pain - so you can live life on your terms.

Typically well tolerated with only occasional mild side-effects.

No opioid
ingredients.

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getting started

What to Expect

ANSWERS

FAQ's

What is Low Dose Naltrexone (LDN)?

LDN is a very low dose of a long-used medication that helps your body boost its own endorphins and calm inflammation. It works by briefly blocking certain receptors, which “resets” how your immune and nervous systems communicate. In low doses (typically 3 to 4.5 mg), it supports pain relief, immune balance, and energy without being habit-forming.

LDN is used for many inflammatory and immune-related conditions, including fibromyalgia, chronic pain, autoimmune issues (such as Hashimoto’s thyroiditis, multiple sclerosis, Crohn’s disease), chronic fatigue, and even long-haul post-viral symptoms. Every person’s response is unique, so your clinician will tailor treatment to your needs.
Note that LDN is not approved by the FDA for any use and is considered “off-label”

No. LDN contains no opioid ingredients and is not addictive. In fact, it blocks opioid receptors rather than stimulating them, which is partly how it helps reset your body’s pain-response system.

Regular naltrexone is prescribed at 50 mg or higher to treat alcohol or opioid dependence. Low Dose Naltrexone uses about one-tenth (or less) of that amount, creating a very different biological effect — gentle immune modulation instead of full receptor blockade.

It’s simple.  Meet with a licensed clinician via telehealth who may issue a prescription that will be filled and shipped by a licensed pharmacy.

Some people notice small improvements — better sleep, calmer mood, steadier energy — within 2–4 weeks.

Pain and inflammation often continue to improve gradually over 6–12 weeks as your body adjusts.

Improvements with LDN can be very subtle.  We recommend giving LDN at least 6 months on the full dose (4.5mg/d) before deciding on whether to stop or continue

Most patients begin at 1.5 mg nightly for two weeks, then gradually increase to 3 mg and eventually 4.5 mg if tolerated. Sensitive or elderly patients may start at 0.5 mg. Your clinician will guide the exact schedule.

LDN is generally well-tolerated. The most common early effects — vivid dreams, mild sleep changes, or temporary fatigue — usually fade within 1–2 weeks.

If anything feels uncomfortable or persists, your clinician can adjust your timing or dose.

Usually yes. LDN plays well with most medications, including thyroid or autoimmune treatments.
However, it cannot be used at the same time as opioid pain medicines, since they cancel each other out. Your clinician will review all your medications before prescribing and let you know if there are any major interactions.

For most patients, no routine labs are required. If you have liver or kidney concerns, your clinician may recommend simple baseline tests to verify normal function.

At this time, compounded LDN is typically not covered by insurance, but TakeBack tries to make LDN as affordable as possible. 

You can often use HSA or FSA funds for both the visit and prescription.

LDN isn’t well studied during pregnancy or breastfeeding, so it’s usually paused during that time.
Always let your clinician know if you become pregnant or are planning to conceive.

You’ll need to pause LDN at least 48 hours before taking any opioid-containing medication or undergoing a procedure that may require opioids.
After your last opioid dose, you can safely restart LDN within 48 hours.

Yes. Research and decades of clinical experience show excellent long-term safety.
Because LDN is non-addictive and metabolized cleanly by the liver, it can be continued for years under supervision.

Yes. There’s no withdrawal or dependency. If you ever need to pause, simply stop — your clinician can help you restart later at a comfortable dose.  You may want to consider weaning off out of an abundance of caution

That’s common. LDN works gradually, helping your immune and nervous systems recalibrate.
Consistency matters — most patients see meaningful benefit after 6–8 weeks of steady use – but can takes 6 months in some patients.

Each prescription is filled by a licensed U.S. compounding pharmacy, using pure naltrexone powder and inert fillers such as cellulose or sucrose.   Your clinician can request specific fillers if needed – just let us know and we can let you know if we can accommodate.

Yes — and some may enhance results. Magnesium, omega-3s, and vitamin D often complement LDN’s effects.
Avoid taking LDN simultaneously with sedatives or sleep aids unless your clinician approves timing adjustments.

Your initial visit covers your first 3 months. You’ll complete a quick online check-in to confirm progress, side effects, and dosing before each renewal.
Most patients renew every 3 months, with a longer review at 6–12 months.

You can always message your care team through your patient portal.
For urgent concerns (such as allergic reactions or new medications), contact us promptly or seek in-person care.

There’s no fixed duration. Some people continue indefinitely for chronic conditions; others taper once symptoms stabilize.
Your clinician will review benefits and goals with you every 6–12 months.

You can explore summaries and research reviews from reputable sources such as:

  • LDN Research Trust
  • PubMed clinical studies (search “low dose naltrexone”)
  • National Institutes of Health (NIH) databases

We combine expert clinician guidance with fast telehealth access and trusted compounding partners.
That means you get LDN safely, quickly, and with real follow-up — not a one-time prescription.

Meet with a licensed clinician via telehealth who may issue a prescription that will be filled and shipped by a licensed pharmacy

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